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Predictions against the spread for college football's Week 5 games.

College football picks against the spread for Week 5 games

James Parks

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Sep 25, 2025

Sep 13, 2025; South Bend, Indiana, USA; Texas A&M Aggies running back Le'Veon Moss (8) runs the ball during the second half against the Notre Dame Fighting Irish at Notre Dame Stadium. Mandatory Credit: Michael Caterina-Imagn Images

Texas A&M RB Le'Veon Moss Throws Shade at Notre Dame Fan Base

Aaron Raley

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Sep 25, 2025

Sep 20, 2025; South Bend, Indiana, USA; Notre Dame Fighting Irish head coach Marcus Freeman celebrates a turnover by the defense against the Purdue Boilermakers during the first half at Notre Dame Stadium.

Notre Dame Commit Trolls Flip Rumors in Viral Response

Nick Shepkowski

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Sep 25, 2025

Arkansas Razorbacks quarterback Taylen Green dropping back to pass against the Ole Miss Rebels at Vaught-Hemingway Stadium in Oxford, Miss.

Three storylines for first meeting between Razorbacks, Fighting Irish

Jacob Davis

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Sep 25, 2025

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Notre Dame linebacker Jaiden Ausberry celebrates assisting with a sack during the second half of a NCAA football game against Purdue at Notre Dame Stadium on Saturday, Sept. 20, 2025, in South Bend.

Notre Dame vs Arkansas: Irish Confidences

John Kennedy

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Sep 25, 2025

Arkansas Razorbacks quarterback Taylen Green throws a pass against the LSU Tigers at Razorback Stadium in Fayetteville, Ark.

An honest look at what Hogs, Irish bring to Saturday's game

Kent Smith

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Sep 25, 2025

Notre Dame quarterback CJ Carr throws a pass in the second half of a NCAA football game against Texas A&M at Notre Dame Stadium on Saturday, Sept. 13, 2025, in South Bend.

Notre Dame's Offense Has Become Unstoppable. Can It Keep Going?

John Kennedy

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Sep 25, 2025

Notre Dame head coach Marcus Freeman celebrates after an interception by cornerback Christian Gray during the first half of a NCAA football game against Purdue at Notre Dame Stadium on Saturday, Sept. 20, 2025, in South Bend.

Marcus Freeman Feeling The Frustration With the Notre Dame Defense

John Kennedy

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Sep 25, 2025

Notre Dame cornerback Dallas Golden (14) and cornerback Christian Gray (6) celebrate a Golden interception during the second half of a NCAA football game against Purdue at Notre Dame Stadium on Saturday, Sept. 20, 2025, in South Bend.

Notre Dame Beats Purdue: Key Takeaways From the Huge Win

John Kennedy

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Sep 25, 2025

Notre Dame head coach Marcus Freeman, left, celebrates with quarterback CJ Carr (13) after winning a NCAA football game 56-30 against Purdue at Notre Dame Stadium on Saturday, Sept. 20, 2025, in South Bend.

What Notre Dame Must Do to Beat Arkansas

John Kennedy

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Sep 25, 2025

College Football Week 5 Picks

First to Forde: Best Picks Against the Spread for College Football Week 5

Iain MacMillan, Pat Forde

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Sep 24, 2025

Notre Dame head coach Marcus Freeman looks on in the second half of a NCAA football game against Texas A&M at Notre Dame Stadium on Saturday, Sept. 13, 2025, in South Bend.

Notre Dame vs Arkansas: Must-Win Clash to Keep Playoff Hopes Alive

John Kennedy

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Sep 23, 2025

Sep 13, 2025; Oxford, Mississippi, USA; Arkansas Razorback head coach Sam Pittman reacts during the first quarter at Vaught-Hemingway Stadium.

Arkansas Head Coach Sam Pittman Discusses All Things Notre Dame Ahead of Matchup

Nick Shepkowski

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Sep 23, 2025

Notre Dame Fighting Irish vs. Arkansas Razorbacks game prediction, odds 2025

Notre Dame vs. Arkansas prediction, odds 2025: Where the experts see an edge

James Parks

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Sep 23, 2025

Sep 13, 2025; West Lafayette, Indiana, USA; Southern California Trojans head coach Lincoln Riley stands on the sidelines during the first quarter against the Purdue Boilermakers at Ross-Ade Stadium. Mandatory Credit: Marc Lebryk-Imagn Images

USC Trojans Hot Start Teases Big Ten Title Contention

Teddy King

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Sep 23, 2025

Alabama running back Richard Young runs against LSU linebacker Whit Weeks in their 2024 game.

Forde-Yard Dash: Dropping Alabama-LSU Heavyweight Clash Is Most Painful Rivalry Loss

Pat Forde

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Sep 22, 2025

Notre Dame handled Purdue in Week 4 to get its first win of the season.

College Football Bowl Projections After Week 4: Alabama vs. Notre Dame in Blueblood Battle

Bryan Fischer

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Sep 22, 2025

Sep 20, 2025; South Bend, Indiana, USA; Notre Dame Fighting Irish head coach Marcus Freeman celebrates a turnover by the defense against the Purdue Boilermakers during the first half at Notre Dame Stadium.

Notre Dame’s Marcus Freeman Addresses Concerns Over Defensive Play Calling

Nick Shepkowski

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Sep 22, 2025

Sep 20, 2025; South Bend, Indiana, USA; Notre Dame Fighting Irish defensive coordinator Chris Ash shouts towards the field against the Purdue Boilermakers during the first half at Notre Dame Stadium.

Notre Dame’s Defensive Struggles Continued Against Purdue

John Kennedy

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Sep 22, 2025

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