Lions' 2025 Schedule Released: Game-by-Game Predictions

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The Detroit Lions' 2025 schedule has officially been released.
Detroit's slate for the upcoming season includes eight home games and nine road games, with primetime matchups sprinkled throughout. The Lions are one of three teams to play on both Thanksgiving and Christmas, meaning they are one of the league's top attractions.
With the NFL schedule officially unveiled, here is Lions OnSI's first game-by-game prediction for the Lions' 2025 season.
Week 1 - Sunday, Sept. 7 -- at Packers (4:25 p.m. ET)
Prediction: 30-23 win (1-0).
Week 2 - Sunday, Sept. 14 -- vs. Bears (1 p.m. ET)
Prediction: 35-20 win (2-0)
Week 3 - Monday, Sept. 22 -- at Ravens (8:15 p.m. ET)
Prediction: 28-27 loss (2-1)
Week 4 - Sunday, Sept. 28 -- vs Browns (1 p.m. ET)
Prediction: 38-14 win (3-1)
Week 5 - Sunday, Oct. 5 -- at Bengals (4:25 p.m. ET)
Prediction: 35-24 loss (3-2)
Week 6 - Sunday, Oct. 12 -- at Chiefs (8:20 p.m. ET)
Prediction: 27-23 win (4-2)
Week 7 - Monday, Oct. 20 -- vs. Buccaneers (7 p.m. ET)
Prediction: 28-21 win (5-2)
Week 8 - BYE
Week 9 - Sunday, Nov. 2 -- vs. Vikings (1 p.m. ET)
Prediction: 27-17 win (6-2)
Week 10 - Sunday, Nov. 9 -- at Commanders (4:25 p.m. ET)
Prediction: 31-28 loss (6-3)
Week 11 - Sunday, Nov. 16 -- at Eagles (8:20 p.m. ET)
Prediction: 34-23 loss (6-4)
Week 12 - Sunday, Nov. 23 -- vs. Giants (1 p.m. ET)
Prediction: 42-20 win (7-4)
Week 13 - Thursday, Nov. 27 -- vs. Packers (1 p.m. ET)
Prediction: 27-23 win (8-4)
Week 14 - Thursday, Dec. 4 -- vs. Cowboys (8:15 p.m. ET)
Prediction: 31-13 win (9-4)
Week 15 - Sunday, Dec. 14 -- at Rams (4:25 p.m. ET)
Prediction: 28-23 loss (9-5)
Week 16 - Sunday, Dec. 21 -- vs. Steelers (4:25 p.m. ET)
Prediction: 28-13 win (10-5)
Week 17 - Thursday, Dec. 25 -- at Vikings (4:30 p.m. ET)
Prediction: 38-35 win (11-5)
Week 18 - TBD -- at Bears -- TBD
Prediction: 31-27 loss (11-6)
Final Lions 2025 record: 11-6
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John Maakaron has covered Detroit Sports since 2013. Brings a vast array of experience covering the Detroit Tigers, Detroit Lions, Michigan Wolverines, Michigan State Spartans, Detroit Mercy Titans, and Oakland University Golden Grizzlies. John brings a wealth of sports broadcast experience. In 2013, John had the vision to establish the Detroit Sports Podcast Network. Has recorded over 3000 podcasts analyzing Detroit Sports. In 2019, Sports Illustrated Media Group, a historical sports media outlet, partnered with Detroit Sports Podcast to provide daily Lions content for their growing and expanding digital media outlet. Our Lions content can also be read in the newspaper at The Oakland Passionate about Detroit Sports and it is reflected in his coverage of the local teams!