Cubs vs. Reds Prediction, Odds, Probable Pitchers, Prop Bets for Friday, July 10

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The Chicago Cubs need to string some wins together in a hurry if they want to close the gap on the Milwaukee Brewers for the top spot in the National League Central.
They have a chance to do exactly that when they take on the 42-50 Cincinnati Reds in a weekend series.
Let's dive into the odds and my best bets for Friday night's opener.
Cubs vs. Reds Odds, Run Line, and Total
Run line
- Cubs -1.5 (+140)
- Reds +1.5 (-170)
Moneyline
- Cubs -110
- Reds -106
Total
- OVER 9.5 (-104)
- UNDER 9.5 (-118)
Cubs vs. Reds Probable Pitchers
- Chicago: Shota Imanaga, LHP (5-7, 4.38 ERA)
- Cincinnati: Hunter Greene, RHP (0-1, 21.60 ERA)
Cubs vs. Reds How to Watch
- Date: Friday, July 10
- Time: 7:10 p.m. ET
- Venue: Great American Ball Park
- How to Watch (TV): Marquee Sports Network, Reds.TV
- Cubs record: 52-41
- Reds record: 42-50
Cubs vs. Reds Best MLB Prop Bet
- Sal Stewart Home Run (+340)
In today's edition of Daily Dinger, I wrote about why I'm betting on Sal Stewart of the Reds to hit a home run:
The Cincinnati Reds are set to take on a lefty starting pitcher in Shota Imanaga, who has a 4.28 ERA while giving up 1.8 home runs per nine innings pitched. That should lead us to betting on a hitter who's been great against lefties this season. Sal Stewart is one of those hitters, as his slugging percentage this season improves from .460 against right-handed pitchers to .523 against left-handed pitchers.
It also helps that the Cubs' bullpen has the highest home runs allowed rate in the Majors at 1.5. All those signs point to Stewart being a great home run bet tonight at +340.
Cubs vs. Reds Prediction and Pick
Don't let Hunter Greene's 21.60 ERA scare you away too much from betting on the Reds. His first start of the season was a disaster, allowing eight earned runs in just 3.1 innings, but I expect a much better outing from him in his second start.
He should be poised for a bounce-back start now that he gets to face a Cubs' lineup that thrives when facing lefties, but regresses when facing right-handed pitchers. Meanwhile, the Reds get to face a lefty in Imanaga, who has surprisingly struggled at times in 2026.
I'll back the Reds as slight home underdogs in this NL Central duel.
Pick: Reds -106 via FanDuel
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Originally from Nova Scotia, Iain MacMillan is a senior editor covering betting, with a focus on NFL, NHL, and golf. He hosts the Bacon Bets Podcast and has been featured on VSIN, BetQL and Monumental Sports Network. He is a member of the Metropolitan Golf Writers Association and his beloved Falcons and Maple Leafs break his heart on a yearly basis.
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