Predicting Every 49ers Game Score Even Though It's Way Too Early

A prediction.

Feb 8, 2026; Santa Clara, CA, USA; NBC Sports analyst Kyle Shanahan prior to the New England Patriots game against the Seattle Seahawks in Super Bowl LX at Levi's Stadium. Mandatory Credit: Mark J. Rebilas-Imagn Images | Mark J. Rebilas-Imagn Images

The San Francisco 49ers’ 2026 NFL schedule is finally out for the world to see, so naturally it is time for the annual way-too-early game-by-game predictions before OTAs and training camp have even begun.

Week 1 vs Los Angeles Rams: Rams 27-20 49ers

A close game to start the season, but victory for the Rams at the Melbourne Cricket Ground.

Week 2 vs Miami Dolphins: 49ers 30-14 Dolphins

The Miami Dolphins are in a rebuild, so the 49ers should win this one.

Week 3 vs Arizona Cardinals: 49ers 35-7 Cardinals

One of the easier matchups for the 49ers. The Arizona Cardinals are the worst team in the NFC West.

Week 4 vs Denver Broncos: Broncos 23-10 49ers

The Denver Broncos are one of the strongest teams in the league. They made it to the AFC Championship Game last season with an incredible defense. This will be a tough ask for the 49ers.

Week 5 vs Seattle Seahawks: Seahawks 27-14 49ers

Another tough test for the 49ers, facing a team that dominated them in the divisional round of the playoffs last season. It might be closer this time, but the 49ers aren't on the Seahawks' level yet.

Week 6 vs Washington Commanders: 49ers 24-10 Commanders

Back to winning ways.

Week 7 vs Atlanta Falcons: 49ers 31-10 Falcons

Two winnable games in a row before the bye week.

Week 8 BYE

Week 9 vs Las Vegas Raiders: 49ers 28-14 Raiders

Refreshed and ready against a team that isn't that competitive, despite a decent 2026 draft.

Week 10 vs Dallas Cowboys: 49ers 27-24 Cowboys

A must-win. While the 49ers don't have the home advantage, they can beat the Dallas Cowboys anywhere. A one-possesion game, but a 49ers win.

Week 11 vs Minnesota Vikings: 49ers 30-17 Vikings

The Minnesota Vikings are in a mess, so should be a victory.

Week 12 vs Seattle Seahawks: Seahawks 24-21 49ers

Home advantage will help, but a narrow defeat against the reigning Super Bowl champions.

Week 13 vs New York Giants: 49ers 30-13 Giants

Their only victory in December. The MetLife Stadium is cursed, so coming away healthy would feel like another victory.

Week 14 vs Los Angeles Rams: Rams 30-28 49ers

Close, but no cigar. The Rams complete the sweep.

Week 15 vs Los Angeles Chargers: Chargers 24-21 49ers

A close game again, but the Chargers will win. This matchup will feel like a Super Bowl for Jim Harbaugh.

Week 16 vs Kansas City Chiefs: Chiefs 28-21 49ers

Kyle Shanahan hasn't won against the Kansas City Chiefs as head coach. That record will continue.

Week 17 vs Philadelphia Eagles: 49ers 28-18 Eagles

Back to winning ways at Levi's Stadium. At the most important time.

Week 18 vs Arizona Cardinals: 49ers 35-10 Cardinals

A win to close out the regular season.

49ers' 2026 NFL Record: 10-7