How Critical Week 10 Matchup Could Swing Rams Playoff Hopes

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It's a bit weird to think of the fact that the Los Angeles Rams, a 6-2 team so far in the 2025 NFL season, are entering into a critical matchup in Week 10. Their upcoming game is a pivotal one for a few different reasons. Firstly, they take on the San Francisco 49ers, a divisional rival of theirs in the NFC West.
This is also a rematch, as the Rams already lost to the Niners in Week 5, 26-23 in overtime. Getting swept by San Francisco in any given year would be devastating. Doing so in a season when both teams are practically neck-to-neck in the standings and pushing for playoff bids would be especially deflating.
So, despite their 6-2 mark, the Rams have to ensure that they take care of business against the Niners and even the season series. They saw firsthand last year how crucial tiebreakers can be in a competitive division, as they sneaked into the playoffs over the Seattle Seahawks due to a rarely seen "strength of victory" tiebreaker. They'll want to avoid losing out to San Francisco in seeding due to the head-to-head record.

Week 10 could be a huge swing for the Rams
Obviously, any win will increase a team's playoff chances, no matter how slim or secure they might be, unless they're mathematically eliminated or guaranteed a postseason bid already. In the same vein, a loss will make it less likely that the loser can advance. However, few individual games will have as great an impact as the Los Angeles Rams' upcoming bout with the San Francisco 49ers.
The NFC playoff race is absolutely brutal. There are ten teams in the conference that are at least .500 this season, going into Week 10. The NFC West picture is even more crowded, with three different organizations boasting six wins already: the Rams, the Niners, and the Seattle Seahawks.
-- WEEK 10 #NFL 🏈 Playoff Leverage --
— Sebastian (@mrcaseb) November 4, 2025
Here you can see how the playoff probability of each team changes depending on whether they win or lose the next game. pic.twitter.com/L16J5YYq6h
That's what makes LA's upcoming rematch with San Francisco so imperative. A recently released predictive model stated that the Rams could improve their chances of making the playoffs to 93 percent with a win over the Niners, while a loss would drop them to 74 percent. Conversely, San Francisco would move to 89 percent by sweeping LA this season, but allowing the Rams to tie the season series would move the Niners back to just 63 percent.
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Andy Quach is a journalism graduate from Florida Gulf Coast University with extensive experience covering the NFL, NBA, and college sports. He is the assistant beat writer for the Jacksonville Jaguars Om SI, and also serves as the fantasy sports and betting reporter for four NFL teams.