Cardinals vs 49ers Broadcast Team Revealed

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The Arizona Cardinals and San Francisco 49ers both hope to emerge to 3-0 to begin the 2025 season, though the NFC West rivals stand in each other's way of doing just that on Sunday.
Arizona is 2-0 for the first time since 2021 while the Niners have now done so in the last three-of-five seasons.
With their tilt coming in the late window of games (1:25 PM kickoff MST in Santa Clara), FOX will show their matchup and the Dallas Cowboys vs Chicago Bears meeting at the same time.
Adam Amin and Mark Sanchez will be in the booth calling the Cardinals-49ers game.
Majority of the country will be watching Dallas vs Chicago (red area) in the FOX late game slate. Blue areas will see Cardinals vs 49ers in Week 3. pic.twitter.com/6N4N86T5gh
— Donnie Druin (@DonnieDruin) September 20, 2025
READ: Cardinals Roster Moves Put Doubt Around Star's Availability
CBS, meanwhile, is also showing two afternoon games, as the Denver Broncos travel to face the Los Angeles Chargers while the Seattle Seahawks play host to the New Orleans Saints.
Cardinals Face 49ers in Week 3
Ahead of their matchup, Cardinals head coach Jonathan Gannon met with reporters and answered a few questions on San Francisco this week:
On 49ers RB Christian McCaffrey:
“Yeah, he is a game changer. We talked about that in the meeting today. He’s a really good football player, both in the run and pass game. He's hard to tackle. He’s got great vision, great acceleration and he can hit home runs. He is a matchup nightmare. He's one of the premier guys in this league and I think offensively how they use him is very creative and cutting edge and it can cause some problems, there's no doubt. We have to be very aware of where he is when they deploy him in different ways. Who's on him and where your help is. We definitely have to have a plan for him.”
On whether the familiarity with the 49ers as a divisional opponent provides any benefit:
“A little bit, but (San Francisco 49ers Head Coach) Kyle (Shanahan), he's always going to change and adapt to who he's playing and what he thinks is the best way to go about it. There'll be some things that we haven't seen on tape, even playing them for however many years now that we've been here. Plus, these last two games, you're going to get some wrinkles.”
On 49ers QB Mac Jones:
“I thought he played well last game. He's obviously smart. He’s got talent. Obviously, where he was drafted and what he’s done in his career already. Quick processor, accurate and more mobile than you think. He'll stand in there, take shots and deliver the football accurately. He played well.”
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Donnie Druin is the Publisher for Arizona Cardinals and Phoenix Suns On SI. Donnie moved to Arizona in 2012 and has been with the company since 2018. In college he won "Best Sports Column" in the state of Arizona for his section and has previously provided coverage for the Pittsburgh Steelers and Arizona State Sun Devils. Follow Donnie on Twitter @DonnieDruin for more news, updates, analysis and more!
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