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Colts Get Fantastic News on Alec Pierce for Cardinals Clash

The Indianapolis Colts ruled out two players ahead of their Week 6 game against the Arizona Cardinals.
Indianapolis Colts wide receiver Alec Pierce (14) catches a pass Sunday, Sept. 14, 2025, during a game against the Denver Broncos at Lucas Oil Stadium in Indianapolis.
Indianapolis Colts wide receiver Alec Pierce (14) catches a pass Sunday, Sept. 14, 2025, during a game against the Denver Broncos at Lucas Oil Stadium in Indianapolis. | Grace Hollars/IndyStar / USA TODAY NETWORK via Imagn Images

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The Indianapolis Colts have released their final injury report ahead of a Week 6 battle vs. the Arizona Cardinals this weekend.

The Colts will be getting a key playmaker back on offense, but have ruled out two players ahead of Sunday's clash.

Colts' Injury Report

Moore, a veteran corner and captain of the defense, will miss his third straight game due to an Achilles injury he suffered against the Tennessee Titans. The team opted not to place Moore on IR, but he's in danger of missing a fourth game next week anyway.

In other news, Pierce will be making his long-awaited return after a two-week stay in concussion protocol. The Colts have tested both Ashton Dulin and Adonai Mitchell as temporary starters in Pierce's absence, and their roles will likely diminish against the Cardinals this weekend.

Goodson did not play against the Las Vegas Raiders last weekend due to a groin injury he suffered in Week 4 against the Los Angeles Rams. Goodson sat out the first two games of the season too, making this his fourth game missed due to injury.

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Buckner, Ebukam, and Ward all missed some portion or all of Friday's practice due to rest. The Colts have opted to rest their veteran defenders throughout the season, so there's nothing new to see there.

Stewart suffered a bicep injury against the Raiders, but he was a full participant on Wednesday and Friday. The veteran tackle will be ready to go against the Cardinals.

Lewis was too sick to practice on Wednesday, but the veteran edge rusher was a full participant on Thursday and Friday and will play on Sunday.

Arizona's injury report features starters in wide receiver Zay Jones, cornerback Max Melton, quarterback Kyler Murray, defensive lineman Darius Robinson, and linebacker Mack Wilson Sr.

Cardinals' Injury Report

  • P Blake Gillikin (Back) - OUT
  • DL Bilal Nichols (NIR-Personal) - OUT
  • WR Zay Jones (Knee) - Questionable
  • CB Max Melton (Hamstring) - Questionable
  • QB Kyler Murray (Foot) - Questionable
  • LB Cody Simon (Knee) - Questionable
  • LB Mack Wilson Sr. (Ankle) - Questionable
  • DL Darius Robinson (Pectoral) - OUT

The most prominent of the lot for Arizona, QB Murray finally put in his first practice of the week after sitting out the first two due to a foot injury. Head coach Jonathan Gannon said that the team is taking it "day-to-day" with Murray's injury.

If Murray can't go, backup quarterback Jacoby Brissett will be the starter, pitting him against his former team at Lucas Oil Stadium.

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Sean Ackerman
SEAN ACKERMAN

Sean Ackerman is the co-Deputy Editor of Indianapolis Colts on SI. Ackerman, a graduate of Western Kentucky University, majored in broadcasting. He's in his third year covering the NFL.