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Buffalo Bills' fans, otherwise known as Bills Mafia, celebrate a touchdown against the Detroit Lions during the first half of an NFL game at the new Highmark Stadium in Orchard Park, NY, on Thursday, Sept. 17, 2026.

Retired NFL quarterback Russell Wilson revealed on CBS' pregame show on Sunday that he believes Buffalo will finally get back into the Super Bowl in February 2027.

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Buffalo Bills safety Sam Franklin Jr. high fives fans while exiting the field after the game against the Houston Texans.

Sam Franklin was fined for a penalty during the Buffalo Bills Week 1 victory and his penalty could come into play down the road as well.

Oregon Ducks defensive lineman Bear Alexander celebrates fumble recovery as the Oregon Ducks host the Oregon State Beavers.

The Buffalo Bills bring in a powerful defensive tackle capable of pushing the pocket in a new 2027 NFL mock draft from Todd McShay.

Sep 15, 2024; Houston, Texas, USA; Houston Texans defensive end Mario Edwards Jr. (97) reacts after sacking Chicago Bears quarterback Caleb Williams (18) (not pictured)

The Buffalo Bills' quarterback avoided a potential serious injury in Week 1, and the NFL has further penalized the offender.

Buffalo Bills wide receiver DJ Moore (2) reacts to his touchdown against the Houston Texans in the third quarter at Reliant Stadium. Mandatory Credit: Thomas Shea-Imagn Images

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Buffalo Bills wide receiver DJ Moore and defensive tackle Ed Oliver have a chance to play in Week 3 based on the reporting from NFL Network's Ian Rapoport.

Dec 14, 2025; Foxborough, Massachusetts, USA; Buffalo Bills quarterback Josh Allen (17) walks off of the field after a game against the New England Patriots during the second half at Gillette Stadium.

The Buffalo Bills are off on Sunday, but there are three NFL games that Western New York football fans should keep an eye on throughout the day.

Buffalo Bills tight end Dawson Knox (88). Hauls in a pass under Jacksonville Jaguars safety Andrew Wingard (42) during the fourth quarter in an NFL football AFC Wild Card playoff matchup, Sunday, Jan. 11, 2026, in Jacksonville, Fla. Bills lead 10-7 at the half over the Jaguars.

The Buffalo Bills are leaning heavily on multiple tight ends and a second-year defensive lineman through two games under rookie head coach Joe Brady.

Sep 17, 2026; Orchard Park, New York, USA; Buffalo Bills wide receiver Keon Coleman (0) runs against the Detroit Lions during the first half at New Highmark Stadium.

The third-year wide receiver didn't have the highest yardage total of his career, but his performance on the field against Detroit may have been his most consistent as a professional.

Sep 17, 2026; Orchard Park, New York, USA; Detroit Lions linebacker Derrick Barnes (55) tackles Buffalo Bills wide receiver D.J. Moore (2) during the first half at New Highmark Stadium.

The Buffalo Bills dodged a bullet with D.J. Moore’s shoulder. But what will their passing offense look like if he is to miss their Week 3 matchup against the Los Angeles Chargers?

Buffalo Bills linebacker Greg Rousseau reacts during the first half against the Detroit Lions at New Highmark Stadium.

Who stood out as the top five and bottom five graded players for the Buffalo Bills during their home opener against the Lions?

Buffalo Bills quarterback Josh Allen winds down the clock and smiles as the fourth quarter goes to the end with then Bills winning 41-31 in their home opener game against the Detroit Lions on Sept. 17, 2026.

The Buffalo Bills answered the bell on a short week, cruising past the Detroit Lions on Thursday Night Football. Now, it's time for rest and recovery.

Detroit Lions' quarterback Jared Goff keeps the ball and runs away from Buffalo Bills' defensive tackle DeWayne Carter during the second half at the Bills' home opener game against the Lions on Sept. 17, 2026.

Micah Hyde said Buffalo's defense struggles because of the pressure quarterback Josh Allen puts on them late in games.

Sep 17, 2026; Orchard Park, New York, USA; Buffalo Bills quarterback Josh Allen (17) is interviewed after the game against the Detroit Lions at New Highmark Stadium.

Buffalo Bills' QB Josh Allen was apparently fighting the flu during his unprecedented Thursday Night Football performance against the Detroit Lions.

Buffalo Bills running back James Cook III runs against the Detroit Lions during the second half at New Highmark Stadium.

Here's who stood out as winners and losers for the Buffalo Bills as they defeated the Detroit Lions in Week 2.

Sep 13, 2026; Houston, Texas, USA; Buffalo Bills defensive tackle Ed Oliver (91) before the game against the Houston Texans at Reliant Stadium.

The Buffalo Bills are hoping to have avoided a potential long-term absence for their franchise defensive tackle.

Buffalo Bills head coach Joe Brady is relaxed on the sidelines before the Bills home opener game against the Detroit Lions.

The Buffalo Bills defeated the Detroit Lions on Thursday Night Football and head coach Joe Brady made history in the process.

Buffalo Bills wide receiver DJ Moore (2) runs against Detroit Lions linebacker Derrick Barnes (55) during the first half at New Highmark Stadium. Mandatory Credit: Mark Konezny-Imagn Images

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Buffalo Bills wide receiver DJ Moore has dodged a bullet based on the latest injury update after his early exit from the Week 2 win over the Detroit Lions.

Buffalo Bills quarterback Josh Allen runs against the Detroit Lions during the first half at New Highmark Stadium.

Here are the biggest takeaways from the Buffalo Bills Thursday Night Football win over the Detroit Lions in Week 2.

Detroit Lions LB Derrick Barnes tackles Buffalo Bills WR DJ Moore during the first half at New Highmark Stadium.

Buffalo Bills WR DJ Moore suffered a shoulder injury during their Thursday night showdown with the Detroit Lions.

Buffalo Bills defensive tackle Ed Oliver before the game against the Houston Texans at Reliant Stadium.

Ed Oliver is among the inactive players for the Buffalo Bills as they host the Detroit Lions in Week 2 of the 2026 season.

Jan 17, 2026; Denver, CO, USA; Buffalo Bills tight end Dalton Kincaid (86) celebrates after a touchdown against Denver Broncos safety Talanoa Hufanga (9) during the fourth quarter of an AFC Divisional Round playoff game at Empower Field at Mile High.

The Buffalo Bills look like a good bet to have their way passing the football against the Detroit Lions on Thursday night in Orchard Park.

Aug 27, 2026; Orchard Park, New York, USA; Buffalo Bills running back Frank Gore Jr. (20) celebrates after scoring a touchdown against the Pittsburgh Steelers during the second quarter at New Highmark Stadium

The Buffalo Bills made two roster moves prior to Thursday Night Football, elevating a RB and a WR off the practice squad to face the Detroit Lions.

Sep 13, 2026; Houston, Texas, USA; Buffalo Bills quarterback Josh Allen (17) at the line of scrimmage during the game against the Houston Texans at Reliant Stadium.

The Buffalo Bills were doubted last week against the Houston Texans, but Thursday night's home opener is shaping up to be a different story.

Buffalo Bills running back James Cook III (4) runs with the ball against the Houston Texans during the first quarter at Reliant Stadium.

Fantasy football Week 2 start or sit advice for Buffalo Bills running back James Cook, wide receiver DJ Moore and tight end Dalton Kincaid.

Kaylee Hartung moderates a press conference at Phoenix Convention Center.

Looking at who will call the action as well as what uniforms each team will wear as the Buffalo Bills host the Detroit Lions in Week 2.

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Super Bowl Champion QB Boldly Predicts Bills, Josh Allen Will Reach Big Game

Super Bowl Champion QB Boldly Predicts Bills, Josh Allen Will Reach Big Game

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Bills S Sam Franklin Fined Under NFL's New 'Three-Strike' Suspension Rule

Bills 2027 NFL Mock Draft Lands Disruptive Defensive Tackle

NFL Protects Josh Allen, Fining Texans' Pass Rusher for Dirty Hit in Bills' Week 1 Win

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DJ Moore, Ed Oliver Injury Updates Give Hope Buffalo Bills' Stars Will Play in Week 3

Three Week 2 Games for Buffalo Bills' Fans to Watch on Stress-Free NFL Sunday

Buffalo Bills' Week 2 Snap Count Analysis: Joe Brady's Preferences Taking Shape

Bills' WR Keon Coleman Earns Heaps of Praise for Primetime Performance vs. Lions

What Bills' Fans Should Expect if D.J. Moore Misses Week 3 vs. Chargers

Buffalo Bills' Highest And Lowest Graded Players in Week 2 Victory vs. Lions

Forward-Thinking Joe Brady Rewards Bills for Thursday Night Victory With Perfect Gift

Former Bills' Safety Micah Hyde Says Quiet Part Out Loud Regarding Defensive Woes

Flu Symptoms, Lions' Defense Can't Stop Bills' Josh Allen from Historic Run in Week 2

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Ed Oliver Injury Update After Pregame Hip Problem Makes Him Inactive for Bills' Win

Joe Brady Just Accomplished Something No Buffalo Bills Coach Ever Has

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DJ Moore Injury Update Confirms Buffalo Bills' WR Avoided Serious Issue

Biggest Takeaways From Buffalo Bills Week 2 Victory Over Detroit Lions

DJ Moore Injury Update: Latest on Bills WR Following Potential Shoulder Injury

Ed Oliver Unexpectedly Headlines Buffalo Bills' Week 2 Inactives vs. Lions

Three Last-Minute Bills' Player Prop Bets That Bank On Josh Allen Air Show vs. Lions

Buffalo Bills Add RB and WR Reinforcements to Thursday Night Football Roster

NFL Prediction Panel Changes Tune on Bills Entering Thursday Home Opener vs. Lions

Bills' Fantasy Football Start or Sit Week 2: James Cook, Dalton Kincaid, DJ Moore

Announcers, Referees & Jersey Combinations for Bills Week 2 Matchup vs. Lions