Dallas Cowboys vs. Eagles Week 1 odds for 2025 NFL opener

The 2025 NFL regular season will kick off with the Dallas Cowboys vs. Philadelphia Eagles, and the opening betting odds have been released.

Dallas Cowboys linebacker Micah Parsons rushes the passer in the game against the Philadelphia Eagles. / Tim Heitman-Imagn Images

The Dallas Cowboys will open the 2025 NFL regular season against the division rival Philadelphia Eagles. It will be Super Bowl banner night for Philly at Lincoln Financial Field, and a perfect opportunity for the Cowboys to get revenge on the Eagles for last season.

During the 2024 campaign, the Eagles delivered two methodic beatdowns of the Cowboys, outscoring Dallas 75-13.

The Cowboys will hope to avoid embarrassment to start the new year, but the folks in Las Vegas don't seem to have much hope in Dallas getting the job done.

MORE: Micah Parsons reacts to Cowboys' season-opener against hated Eagles

Immediately after the season opener was announced, FanDuel Sportsbook released the opening odds for the game.

Dallas Cowboys quarterback Dak Prescott hugs Philadelphia Eagles quarterback Jalen Hurts. / Tim Heitman-Imagn Images

The Cowboys open as a 6.5-point underdog on the road. Of course, there is plenty of time for the line to change before September.

Game odds refresh periodically and are subject to change. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.

MORE: Cowboys' improved defense ranks inside NFL's top 10 for 2025 season

It's going to be a difficult test to open the season, but one that could benefit the Cowboys in the long run.

Dallas Cowboys linebacker Micah Parsons rushes the passer in the game against the Philadelphia Eagles. / Tim Heitman-Imagn Images

The Cowboys and Eagles will face off at Lincoln Financial Field on Thursday, September 4. Kick off is set for 8:20 p.m. ET on NBC and Peacock.

Get your popcorn ready, because we are about to learn a lot about the Cowboys in the Schottenheimer Era right out of the gate.

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