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The Kansas City Chiefs and quarterback Patrick Mahomes are favored in Week 12.

NFL Week 12 Best Bets (Predictions for Chiefs vs. Colts, Best Total Bet on Sunday)

Peter Dewey, Iain MacMillan

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Nov 22, 2025

Bet on Daniel Jones to score a touchdown against the Chiefs in NFL Week 12 action.

Colts vs. Chiefs Best NFL Prop Bets and Anytime Touchdown Scorer Picks for NFL Week 12

Iain MacMillan

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Nov 22, 2025

Oct 5, 2025; Indianapolis, Indiana, USA; Indianapolis Colts cornerback Charvarius Ward (7) attempts to bring down Las Vegas Raiders Albert Okwuegbunam Jr. (86) during a game at Lucas Oil Stadium. Mandatory Credit: Christine Tannous-USA TODAY Network via Imagn Images

Charvarius Ward Ready to Wreak Havoc for Colts with Sauce Gardner

Drake Wally

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Nov 22, 2025

Nov 16, 2025; Denver, Colorado, USA; Kansas City Chiefs tight end Travis Kelce (87) reacts after his touchdown in the fourth quarter against the Denver Broncos at Empower Field at Mile High.

Three Pivotal Matchups to Watch for in Colts vs. Chiefs

Sean Ackerman

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Nov 22, 2025

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Aug 7, 2025; Philadelphia, Pennsylvania, USA; Cincinnati Bengals wide receiver Cole Burgess (17) in the tunnel against the Philadelphia Eagles at Lincoln Financial Field.

Colts Host Duo of Former AFC Receivers Before Chiefs Clash

Sean Ackerman

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Nov 21, 2025

Oct 5, 2025; Indianapolis, Indiana, USA; Indianapolis Colts safety Cam Bynum (0) high fives cornerback Charvarius Ward (7) after an interception against the Las Vegas Raiders during the second quarter at Lucas Oil Stadium.

Charvarius Ward, Tyquan Lewis Unsure for Colts Clash with Chiefs

Sean Ackerman

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Nov 21, 2025

Nov 9, 2025; Berlin, Germany; Indianapolis Colts running back Jonathan Taylor (28) reacts with teammates against the Atlanta Falcons during the NFL Berlin Game at Olympic Stadium. Mandatory Credit: Kirby Lee-Imagn Images

Colts' Super Bowl Odds Improve Ahead of Make-or-Break Stretch

Michael Greene

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Nov 21, 2025

Nov 2, 2025; Pittsburgh, Pennsylvania, USA; Indianapolis Colts tight end Tyler Warren (84) runs after a catch as Pittsburgh Steelers linebacker Payton Wilson (41) and cornerback Brandin Echols (26) defend during the fourth quarter at Acrisure Stadium. Mandatory Credit: Charles LeClaire-Imagn Images

Colts' Tyler Warren Giving Off 'Pro Bowl Vibes'

Drake Wally

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Nov 21, 2025

Patrick Mahomes and the Kansas City Chiefs are favored against the Indianapolis Colts on Sunday.

Colts vs. Chiefs Final Score Prediction for NFL Week 12 (Can Kansas City Cover?)

Ameer Tyree

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Nov 21, 2025

Indianapolis Colts head coach Shane Steichen walks the sideline during the game Sunday, Oct. 12, 2025, against the Arizona Cardinals at Lucas Oil Stadium in Indianapolis.

How to Watch/Stream/Listen Colts vs. Chiefs

Drake Wally

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Nov 21, 2025

Sep 25, 2022; Indianapolis, Indiana, USA; Kansas City Chiefs quarterback Patrick Mahomes (15) throws for an incomplete pass during a game against the Kansas City Chiefs at Lucas Oil Stadium. Mandatory Credit: Jenna Watson/IndyStar Staff-Imagn Images

Colts Forecasted to 'Blow Out' Chiefs

Drake Wally

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Nov 21, 2025

Jonathan Taylor and the Colts head into Arrowhead Stadium sitting at 8–2.

Key Matchups, Predictions for Colts-Chiefs and More NFL Week 12 Games

Matt Verderame

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Nov 21, 2025

Nov 9, 2025; Berlin, Germany; Indianapolis Colts quarterback Daniel Jones (17) runs the ball against the Atlanta Falcons during the NFL Berlin Game at Olympic Stadium.

Colts' Ward Nearing Return, Daniel Jones Pops Up on Injury Report

Sean Ackerman

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Nov 20, 2025

Marshall Faulk

Southern Jaguars: Why Fans Are Divided On Marshall Faulk! Is He The Answer?

Kyle Mosley

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Nov 20, 2025

Sep 28, 2025; Inglewood, California, USA; Los Angeles Rams wide receiver Davante Adams (17) celebrates after a touchdown in the first half against the Indianapolis Colts at SoFi Stadium. Mandatory Credit: Jayne Kamin-Oncea-Imagn Images

Fantasy Football Week 12 WR/CB Key Matchups: Start Davante Adams, Sit Brian Thomas Jr

Thomas Carelli

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Nov 20, 2025

Indianapolis Colts head coach Shane Steichen walks the field Sunday, Oct. 12, 2025, ahead of the game against the Arizona Cardinals at Lucas Oil Stadium in Indianapolis.

Colts' Shane Steichen Details Approach to Battling Chiefs

Sean Ackerman

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Nov 20, 2025

Oct 26, 2025; Indianapolis, Indiana, USA; Indianapolis Colts tight end Tyler Warren (84) warms up before the game against the Tennessee Titans at Lucas Oil Stadium. Mandatory Credit: Robert Goddin-Imagn Images

Colts vs. Chiefs Best Bets | Back Tyler Warren and Travis Kelce

Michael Greene

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Nov 20, 2025

Oct 26, 2025; Indianapolis, Indiana, USA; Indianapolis Colts head coach Shane Steichen looks on during the second quarter against the Tennessee Titans at Lucas Oil Stadium. Mandatory Credit: Robert Goddin-Imagn Images

Colts' Biggest Hurdle for Playoff Position May Be This Bitter Rival

Drake Wally

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Nov 20, 2025

The Steelers are road underdogs against the Bears in NFL Week 12 action.

NFL Upset Predictions and Picks for Week 12 (Will Bears Luck Run Out vs. Steelers?)

Iain MacMillan

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Nov 20, 2025

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