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Nov 9, 2025; Santa Clara, California, USA; San Francisco 49ers running back Christian McCaffrey (23) walks on the field prior to the game against the Los Angeles Rams at Levi's Stadium.

Christian McCaffrey And 4 Other PrizePicks Lines For MNF: Panthers Vs. 49ers

Ethen Hutton

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Nov 24, 2025

Oct 12, 2025; Charlotte, North Carolina, USA; Carolina Panthers wide receiver Xavier Legette (17) walks off the field during halftime against the Dallas Cowboys at Bank of America Stadium. Mandatory Credit: Scott Kinser-Imagn Images

Perfect Week 12 MNF FanDuel Lineup: Find Juicy Value in Xavier Legette Among Others

Thomas Carelli

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Nov 24, 2025

Oct 12, 2025; Charlotte, North Carolina, USA; Carolina Panthers wide receiver Xavier Legette (17) reacts after missing a catch in the second quarter against the Carolina Panthers at Bank of America Stadium.

Xavier Legette, Ricky Pearsall, and 3 other Underdog Props For 49ers vs. Panthers

Gray Deyo

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Nov 24, 2025

Nov 16, 2025; Atlanta, Georgia, USA; Carolina Panthers kicker Ryan Fitzgerald (10) shakes hands with teammates after scoring the game winning field goal against the Atlanta Falcons at Mercedes-Benz Stadium.

This stat may be a sign the Carolina Panthers are in for tough times ahead

Tim Weaver

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Nov 24, 2025

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The 49ers play the Carolina Panthers on ‘Monday Night Football’ in Week 12 of the NFL slate.

49ers vs. Panthers: Three Bold Predictions for Week 12 ‘Monday Night Football’

Karl Rasmussen, Mike Kadlick

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Nov 24, 2025

Analyst reveals totally inaccurate draft needs for Carolina Panthers

Zach Roberts

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Nov 24, 2025

Nov 9, 2025; Charlotte, North Carolina, USA; Carolina Panthers wide receiver Tetairoa McMillan (4) with the ball as New Orleans Saints safety Justin Reid (21) defends in the third quarter at Bank of America Stadium. Mandatory Credit: Bob Donnan-Imagn Images

Analyst lays out how Panthers can win huge upset over the 49ers

Zach Roberts

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Nov 24, 2025

Nov 16, 2025; Atlanta, Georgia, USA; Carolina Panthers quarterback Bryce Young (9) looks on in the third quarter against the Atlanta Falcons at Mercedes-Benz Stadium. Mandatory Credit: Brett Davis-Imagn Images

49ers' 4th quarter numbers could play right into Panthers QB Bryce Young's hands

Zach Roberts

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Nov 24, 2025

Aug 8, 2025; Charlotte, North Carolina, USA; Carolina Panthers wide receiver Jalen Coker (18) goes in motion during the second quarter against the Cleveland Browns at Bank of America Stadium.

Where the Carolina Panthers are in NFL power rankings going into critical MNF game

Tim Weaver

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Nov 24, 2025

San Francisco 49ers running back Christian McCaffrey is a great prop target in Week 12.

Best NFL Picks and Predictions Today (How to Bet Panthers vs. 49ers on Monday Night Football in NFL Week 12)

Peter Dewey

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Nov 24, 2025

San Francisco 49ers tight end George Kittle is a great prop target in Week 12.

Panthers vs. 49ers Best Anytime Touchdown Scorer Picks for Monday Night Football in NFL Week 12

Peter Dewey

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Nov 24, 2025

Carolina Panthers wide receiver Tetairoa McMillan is a solid prop target in Week 12.

Panthers vs. 49ers Best NFL Prop Bets for Monday Night Football in Week 12 (Bet on Tetairoa McMillan)

Peter Dewey

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Nov 24, 2025

Nov 16, 2025; Atlanta, Georgia, USA; Carolina Panthers quarterback Bryce Young (9) reacts to a touchdown in the fourth quarter against the Atlanta Falcons at Mercedes-Benz Stadium. Mandatory Credit: Brett Davis-Imagn Images

Bryce Young eyes first place, 4 other things to know about Panthers vs. 49ers

Russell Baxter

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Nov 24, 2025

San Francisco 49ers quarterback Brock Purdy.

Panthers vs. 49ers Final Score Prediction for NFL Week 12 (Trust San Francisco?)

Peter Dewey

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Nov 24, 2025

Nov 16, 2025; Atlanta, Georgia, USA; Carolina Panthers running back Rico Dowdle (5) runs with the ball while being defended by Atlanta Falcons cornerback A.J. Terrell Jr. (24) in the first quarter at Mercedes-Benz Stadium. Mandatory Credit: Dale Zanine-Imagn Images

4 bold predictions for Panthers-49ers Monday Night Football matchup

Zach Roberts

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Nov 23, 2025

Oct 5, 2025; Charlotte, North Carolina, USA; Carolina Panthers general manager Dan Morgan on the field before the gsme at Bank of America Stadium.

ESPN NFL analyst shares glowing praise for Carolina Panthers' offseason work

Tim Weaver

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Nov 23, 2025

Aug 12, 2023; Charlotte, North Carolina, USA; Carolina Panthers offensive tackle Taylor Moton (72) during the second half against the New York Jets at Bank of America Stadium.

Panthers vet Taylor Moton talks up an underrated part of Bryce Young's game

Tim Weaver

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Nov 23, 2025

Oct 9, 2022; Charlotte, North Carolina, USA; San Francisco 49ers running back Jeff Wilson Jr. (22) runs for yardage pursued by Carolina Panthers cornerback Jaycee Horn (8) during the first quarter at Bank of America Stadium.

What Jaycee Horn said about the Panthers' rare opportunity vs. 49ers

Tim Weaver

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Nov 23, 2025

Nov 9, 2025; Charlotte, North Carolina, USA; Carolina Panthers wide receiver Tetairoa McMillan (4) during player introductions at Bank of America Stadium.

Panthers rookie Tetairoa McMillan gets horrendous fine from NFL for 'violent' gesture

Tim Weaver

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Nov 23, 2025

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